Presents a collection of tested laboratory protocols for the isolation and characterization of eukaryotic and prokaryotic RNA. This book emphasises on transcript profiling, including quantification issues and elucidation of alternative transcription start sites. It includes classic and contemporary techniques useful for labs.

Due to its prolific reproduction and the external development of the transparent embryo, the zebrafish is the prime model for genetic and developmental studies, as well as research in genomics. Part of the Reliable Lab Solutions series dealing with zebrafish, this title brings together a collection of time-tested methods.

Glycobiology is the study of complex carbohydrates, or glycans, which play an important role in biochemical signalling between and among cells and hence normal cell and tissue function. This book focuses on bioinformatics of carbohydrates and glycoproteins. It provides a comprehensive review of the area, giving an introduction and an overview.

The steps in the translation of the genetic blueprint to the observed phenotype is being understood through proteome, metabolome and phenome analysis, all underpinned by advances in bioinformatics. This book helps understand applied bioinformatics.

Professor Bryan Sykes provides a first-hand account of his research into a gene which passes undiluted from generation to generation through the maternal line and shows how it is being used to track our genetic ancestors.

A supplement for any genetics textbook, this guide gives students thorough instruction and practice for solving genetics problems. Using callout comments, the author walks students through the process of breaking down word problems by dissecting each sentence. At each significant point in the statement of a problem, students learn to evaluate the given data, think about how it fits into the ...

Supplementing analysis techniques in serious crime cases, trace DNA can allow investigation of volume crime cases such as burglary or vehicle theft. However, despite the widespread use of trace DNA, there are very few specific validated methods. This book presents advances in the field of DNA research as an aid in Forensic studies and Genetics.

The most important investigation of genetic science since The Selfish Gene, from the author of the critically acclaimed and best-selling The Red Queen and The Origins of Virtue.

Provides an introduction to genetic analysis. This book covers contemporary genetics, and helps students understand the essentials of genetics, featuring various experiments, teaching them how to analyze data, and how to draw their own conclusions.

RNA interference (RNAi) is a mechanism that inhibits gene expression at the stage of translation or by hindering the transcription of specific genes. This book includes reviews of the broadest interest to geneticists and their colleagues in affiliated disciplines, providing researchers an overview and synthesis of various findings in the area.

Presents an introduction to the algorithmic techniques applied in bioinformatics. For each topic, this title details the biological motivation, defines the corresponding computational problems, and includes examples to illustrate each algorithm.

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Student-focused, robust teaching package, with a strong illustration programme, now including references to software and databases and two new chapters.

This collection of papers summarizes understanding about the extent of genetic variation within wild populations and the ways to monitor such variation. It proposes the idea that an objective of evolutionary ecology is necessary to predict organism, population, community, and ecosystem response.

This significant new publication deals with genomic or parental imprinting.

Presents stem cells and gene therapy together in one comprehensive volume. it also addresses the major advances in stem cell biology research and the many applications of this research in the development of novel molecular therapies.

This volume of papers presented at a genomics conference discusses whether the availability of genome sequence information for humans and other organisms will yield commercial opportunities and if so, how companies could make use of this information.

This volume comprises the 1998 Oxford Amnesty Lectures. Topics discussed include: are eugenics practices morally defensible?; who should have access to genetic information about particular individuals?; and what dangers for cultural and racial diversity do developments in genetics pose?

Mutation detection is increasingly undertaken in a wide spectrum of research areas. This volume offers tried and tested protocols for a range of detection methods, from the labs of researchers in the field.

Tremendous strides in decoding the human genome have been made over the last ten years. Large, chromosome-scale, genome-scale EST-sequencing and mapping techniques have dramatically expanded the base of identified genes and sequenced DNA.