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Tall 8vo.

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Former Library book. Shows some signs of wear, and may have some markings on the inside. Shipped to over one million happy customers. Your purchase benefits world literacy!

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(372 pages) this challenging book reviews modern neurotherapeutics from the point of view of drug targeting. this challenging book reviews modern neurotherapeutics from the point of view of drug targeting, surveying the scientific and clinical basis of drug delivery across biological membranes. it will encourage a wide range of clinicians and neuroscientists to reexamine the use of drugs in treating disorders of the central nervous system. this challenging book reviews modern neurotherapeutics from the point of view of drug targeting, surveying the scientific and clinical basis of drug delivery across biological membranes. it will encourage a wide range of clinicians and neuroscientists to reexamine the use of drugs in treating disorders of the central nervous system. the thesis of this innovative and challenging book is that brain drug development has been restricted by the failure of adequate brain drug targeting, and that this is an increasingly urgent problem as developments in genomics lead to new generations of therapeutic macromolecules. the author, a world leader in the study of the blood-brain barrier and its clinical implications, reviews the field of neurotherapeutics from the point of view of drug targeting. he surveys the scientific and clinical basis of drug delivery across biological membranes, including topics such as ge*n*e*t*ically engineered trojan horses for drug targeting, antisense neurotherapeutics, and gene therapy of brain disorders. at a time when there are few significant new drug treatments in prospect for common neurological diseases, this authoritative review will encourage a wide range of clinicians and neuroscientists to reexamine the development and use of drugs in treating disorders of the central nervous system. preface, 1. drug targeting, drug discovery, and brain drug development, 2. invasive drug delivery, 3. lipid-mediated transport and carrier-mediated transport of small molecules, 4. receptor-mediated transcytosis of peptides, 5. vector discovery: ge*n*e*t*ically-engineered trojan horses for drug targeting, 6. linker strategies: the engineering of multi-functional drug formulations, 7. protein neuropathies and peptide radiopharmaceuticals, 8. antisense neurotherapeutics and imaging gene expression in vivo, 9. gene therapy of the brain, 10. blood-brain barrier genomics, epilogue, bibliography.'...a book that will become a standard on drug targeting to the brain...a must for everybody who works in the field of brain drug delivery in academia as well as in the pharmaceutical industry. ' w. kamphorst, web. bmjbookshop[full stop]com'this book provides an extensive review of brain drug targeting of large molecules and will be a valuable reference to those interested in completing research in this field. ' tejal patel, doody's health sciences book review journal'this is an excellent book to be expected from a major researcher in the field. the lucid text is illuminated by an eclectic mix of diagrams and plates that will have a broad appeal to a wide audience. ' a. davenport, british journal of neurosurgery ()

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0521800773 Good condition. May have some markings & or shelfwear. All pages intact. Used items may not include extras such as infotrac, CD or other web access codes.

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Please note that deliveries to addresses in the UK and Europe will be in 4-14 business days. Other countries should refer to Alibris standard times. In this innovative and challenging book, William Pardridge, a world leader in the study of the blood-brain barrier and its clinical implications, argues that brain drug development has been restricted by the failure of adequate brain drug targeting. This is an increasingly urgent problem as developments in genomics lead to new generations of therapeutic macromolecules. The author reviews the field of neurotherapeutics from the point of view of drug targeting. He surveys the scientific and clinical basis of drug delivery across biological membranes, including topics such as genetically engineered trojan horses for drug targeting, antisense neurotherapeutics, and gene therapy of brain disorders. At a time when there are few significant new drug treatments in prospect for common neurological diseases, this authoritative review will encourage a wide range of clinicians and neuroscientists to reexamine the development and use of drugs in treating disorders of the central nervous system. ISBN10: 0521800773.

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372 p. Contains: Illustrations.

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PLEASE NOTE: All books are promptly imported from the UK using DHL or Royal Mail international mail WITH TRACKING NUMBER. Delivery is typically 5-10 working days. Please do not select expedited shipping. Professional and reliable bookseller (est.1987). This challenging book reviews modern neurotherapeutics from the point of view of drug targeting.

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Brand New. Never Used.

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(NEW TITLE), Size 25cm, pp. 372.

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0521800773 Absolutely Brand New. No marks and in pristine condition. Used items may not include extras such as infotrac, CD or other web access codes.